People are tasing themselves to be more productive. Why? How is this affecting our society? Are there any long-term side effects of tasing ourselves daily at work, school, and home?
“Tasigna lawsuit” is a legal case that was filed against the manufacturer of Tasigna, Teva Pharmaceuticals. The lawsuit alleges that there are long term side effects from using the drug, and it should have been labeled as such.
The medicine Tasigna (nilotinib) is used to treat chronic myeloid leukemia (CML). The medicine has been associated to serious side effects such as clogged arteries, strokes, and even death.
Our lawyers are looking into allegations that Tasigna’s producer, Novartis, was aware of these negative effects but refused to tell the public.
What Is Tasigna and How Does It Work?
Tasigna was authorized by the FDA in 2007 to treat chronic myeloid leukemia with the Philadelphia chromosome (CML). Myleoid stem cells, which ultimately mature into red blood cells, granulocytes, monocytes, or platelets, are affected by CML.
Tasigna belongs to the tyrosine kinase inhibitors family of medicines (TKIs). Gleevec (imatinib), which is also manufactured by Novartis, and Sprycel (dasatinib), which is manufactured by Bristol-Myers Squibb, are two other TKI medicines.
These medications work to cure leukemia by inhibiting tyrosine kinases, a protein that promotes cancer cell proliferation. TKI medications like Tasigna help stop leukemia from spreading by inhibiting this protein.
Tasigna is a twice-daily medicine that is administered orally in the form of capsules.
What Are Some of the Most Common Tasigna Adverse Effects?
Novartis cautions about the following Tasigna negative effects:
- Pain in the muscles and joints
- Sneezing, runny or stuffy nose, aching throat
Tasigna Has Been Linked to Cardiovascular Complications
To far, the FDA has received reports of about 15,500 Tasigna-related adverse events and 2,786 fatalities. Heart attacks were mentioned in almost 500 of these reports, and 273 individuals had strokes after using Tasigna.
QT prolongation, myocardial ischemia, and atherosclerosis are among the other significant cardiovascular adverse effects mentioned.
Prolonging the QT (Long QT syndrome)
“The risk of QT prolongation and sudden mortality associated with nilotinib, albeit uncommon, demands cautious monitoring,” the FDA says.
Tasigna’s relation to QT interval prolongation and sudden mortality prompted the FDA to issue a black box warning, the highest level of caution.
QT interval prolongation is a cardiac rhythm disorder that causes rapid, irregular heartbeats. Fainting, convulsions, and sudden death might occur if the heart does not return to its normal rhythm.
“The possibility for QT prolongation and sudden mortality associated with nilotinib, albeit uncommon, demands attentive monitoring,” the FDA advises on the product label.
Physicians should use electrocardiograms to check the QT interval before starting therapy, seven days after starting treatment, and on a regular basis afterwards, according to the FDA. Patients with low potassium or magnesium levels in their blood are at a higher risk of developing long QT syndrome, and Tasigna is not indicated for them.
Ischemia of the myocardium
The FDA’s adverse event reporting database has received over 100 reports of Tasigna-related myocardial ischemia diagnosis.
A blockage of the coronary arteries is the most common cause of myocardial ischemia. It causes a reduction in blood flow to the heart, which reduces the quantity of oxygen available to the heart.
According to an FDA post-market analysis, 5.8% of Tasigna patients had ischemic heart disease-related events.
277 instances of Tasigna-related atherosclerosis were purportedly documented globally, according to Canadian health authorities.
Atherosclerosis is a disorder in which fatty deposits build up in the arteries and ultimately obstruct them. The flow of blood and oxygen to the cells is steadily reduced in this dangerous illness.
Coronary artery disease, peripheral arterial disease, blood clots, heart attacks, and strokes may all be caused by atherosclerosis. In the developed world, it is presently the top cause of death.
Tasigna products marketed in Canada have been labeled with a warning about the drug’s link to atherosclerosis since 2013. After 277 instances of atherosclerosis were purportedly reported globally, Canadian health authorities changed the label. Despite these studies, lawsuits claim that Novartis never informed of the danger of atherosclerosis in the United States.
Low blood cell counts, decreased blood flow to the heart, lungs, or brain, pancreatitis, and Tumor Lysis Syndrome, a condition that can occur when cancer cells are broken down quickly, resulting in kidney failure or an abnormal heartbeat, are all serious side effects linked to Tasigna, according to the FDA.
Tasigna Causes Heart Complications?
Novartis is being sued by some individuals who took Tasigna and had a heart or circulation issue as a result. Novartis is accused of failing to adequately notify patients about these adverse effects, according to the cases.
You may be eligible to compensation if you or a loved one suffers a cardiac or vascular ailment such as a heart attack, stroke, or atherosclerosis. A lawsuit might help you be paid for medical costs, lost earnings, pain and suffering, and other expenses.
Our class action lawyers have taken on some of the country’s top pharmaceutical firms, and we have the expertise and resources to take on Novartis. We’ve recovered $5 billion for our clients thus far.
For a free, no-obligation case assessment, contact us now. It will never cost you anything until we get a favorable decision or settlement on your behalf.
Tasinga is a new drug that has been released on the market. It is meant to be used as an alternative to pain killers, but there are some long-term side effects of the drug. Reference: tasigna reviews.
Frequently Asked Questions
What happens when you stop taking Tasigna?
Does Tasigna cause weight loss?
A: Tasigna is a medication that has been proven to be very effective in treating cancer. It can help people lose weight by lowering their blood sugar and cholesterol levels.
Can Tasigna cure CML?
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